The staff at BioTechLogic has expertise in the purification of PEGylated and non-PEGylated proteins, antibody fragments, oligonucleotides and blood products. We have developed work processes, provided on-site manufacturing support and designed process steps using the following purification technology expertise:
- Laboratory and industrial-scale liquid chromatography
- High-pressure liquid chromatography
- Ultrafiltration/Diafiltration
- Rotary evaporation
- Sterile filtration
BioTechLogic has experience in the design of unit operations. We provide knowledge and experience using various equipment and operating procedures, and consider validation requirements in the decision-making process.
 BioTechLogic accomplishments include:
- Multiple biopharmaceutical IND filings (cytokines, proteins, antibody fragments) at 10 L to 10,000 L scale
- Pre-Qualification activities for an antibody fragment produced at 10,000 L scale
- RNA oligonucleotide synthesis process performed on solid support system validated and FDA approved for the first synthetically produced oligonucleotide
- NDA approval and MAA positive opinion of a Growth Hormone Receptor Antagonist